For use in horses only


Do not use in horses intended for human consumption.
NSAIDs should not be used concurrently with Tildren. Concurrent use of NSAIDs with Tildren may increase the risk of renal toxicity and acute renal failure.


Buy Tildren is not for human use. Keep this and all drugs out of the reach of children. Consult a physician in case of accidental human exposure.


Federal law restricts this drug to use by or on the order of a licensed veterinarian.


Tildren is indicated for the control of clinical signs associated with navicular syndrome in horses.


Do not use in horses with known hypersensitivity to tiludronate disodium or to mannitol. Do not use in horses with impaired renal function or with a history of renal disease. Bisphosphonates are excreted by the kidney; therefore, conditions causing renal impairment may increase plasma bisphosphonate concentrations resulting in an increased risk for adverse reactions.


Approximately 30-45% of horses administered Tildren will demonstrate transient signs consistent with abdominal pain (colic). Horses should be observed closely for 4 hours post-infusion for the development of clinical signs consistent with colic or other adverse reactions. Colic signs can last approximately 90 minutes and may be intermittent in nature. Hand walking the horse may improve or resolve the colic signs in many cases. If a horse requires medical therapy, non-NSAID treatments should be administered due to the risk for renal toxicity. Avoid NSAID use.

Horses should be well hydrated prior to administration of Tildren due to the potential nephrotoxic effects of Tildren.

Tildren should be used with caution in horses receiving concurrent administration of other drugs that may reduce serum calcium (such as tetracyclines) or whose toxicity may exacerbate a reduction in serum calcium (such as aminoglycosides).

Horses with HYPP (heterozygous or homozygous) may be at an increased risk for adverse reactions, including colic signs, hyperkalemic episodes, and death.
The safe use of Tildren has not been evaluated in horses less than 4 years of age.

Bisphosphonates should not be used in pregnant or lactating mares, or mares intended for breeding. Bisphosphonates have been shown to cause fetal developmental abnormalities in laboratory animals.


A single dose of Tildren should be administered as an intravenous infusion at a dose of 1 mg/kg (0.45 mg/ lb). The infusion should be administered slowly and evenly over 90 minutes to minimize the risk of adverse reactions. Maximum effect may not occur until 2 months post-treatment.

For ADMINISTRATION INSTRUCTIONS (preparation of the reconstituted solution (20mg/mL) and preparation of the solution for infusion) and for complete product information, please read the insert contained within the product packaging.


Sterile powder (not reconstituted): Store at controlled room temperature 68°F-77°F (20°C-25°C). After preparation, the infusion should be administered either within 2 hours of preparation, or it can be stored for up to 24 hours under refrigeration at 36°F-46° F (2°C-8°C) and protected from light.

Return and Refund Policy

Last updated March 07, 2023

Thank you for your purchase. We hope you are happy with your purchase. However, if you are not completely satisfied with your purchase for any reason, you may return it to us for a full refund, store credit, or an exchange. Please see below for more information on our return policy.
All returns must be postmarked within five (5) days of the purchase date. All returned items must be in new and unused condition, with all original tags and labels attached.
To return an item, please email customer service at to obtain a Return Merchandise Authorization (RMA) number. After receiving a RMA number, place the item securely in its original packaging, and mail your return to the following address:
Horse Meds for sale
Attn: Returns
38 Polsted Rd, London SE6 4YQ, United Kingdom
London , London SE6 4YQ
United Kingdom
Return shipping charges will be paid or reimbursed by us. 
After receiving your return and inspecting the condition of your item, we will process your return or exchange. Please allow at least eight (8) days from the receipt of your item to process your return or exchange. Refunds may take 1-2 billing cycles to appear on your credit card statement, depending on your credit card company. We will notify you by email when your return has been processed.
For defective or damaged products, please contact us at the contact details below to arrange a refund or exchange.
If you have any questions concerning our return policy, please contact us at:


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Tildren (tiludronate disodium)
Original price was: 390.00$.Current price is: 319.00$.

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